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Int J Legal Med. 2008 Nov;122(6):449-56. doi: 10.1007/s00414-008-0250-6. Epub 2008 Jun 12.

The effect of number of loci on geographical structuring and forensic applicability of Y-STR data in Finland.

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  • 1Department of Forensic Medicine, University of Helsinki, Helsinki, Finland. jukka.palo@helsinki.fi

Abstract

The Y-chromosomal diversity among Finnish males is characterized by low diversity and substantial geographical substructuring. In a 12-locus data set (PowerPlexY), especially the eastern parts of the country showed low levels of variation, and the western, middle, and eastern parts of Finland differed from each other by their Y-short tandem repeat (STR) haplotype frequencies (Palo et al., Forensic Sci Int Genet 1:120-124, 2007). In this paper, we have analyzed geographical patterns of Y-STR diversity using both 12-locus (PowerPlexY) and 17-locus (Yfiler) data sets from the same set of geographically structured samples. In the larger data set, the haplotype diversity is significantly higher, as expected. The geographical distribution of haplotypes is similar in both data sets, but the level of interregional differences is significantly lower in the Yfiler data. The implications of these observations on the forensic casework are discussed.

PMID:
18548267
DOI:
10.1007/s00414-008-0250-6
[PubMed - indexed for MEDLINE]
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