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PLoS One. 2008 Jun 11;3(6):e2391. doi: 10.1371/journal.pone.0002391.

Serum alpha-fetoprotein predicts treatment outcome in chronic hepatitis C patients regardless of HCV genotype.

Author information

1
Unité d'Epidémiologie des Maladies Emergentes, Institut Pasteur, Paris, France.

Abstract

We examined the association between serum alpha-fetoprotein (AFP) level and sustained virological response (SVR) in 93 chronic hepatitis C patients. The SVR rate was much higher among patients with serum AFP levels below rather than above the median value (5.7 ng/ml) (58.7% and 19.2%, respectively; P<0.0001). Serum AFP should be added to the list of factors predictive of treatment response in chronic hepatitis C.

PMID:
18545682
PMCID:
PMC2398780
DOI:
10.1371/journal.pone.0002391
[Indexed for MEDLINE]
Free PMC Article

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