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J Clin Microbiol. 2008 Aug;46(8):2805-8. doi: 10.1128/JCM.00071-08. Epub 2008 Jun 4.

Characterization of clonal relatedness among the natural population of Staphylococcus aureus strains by using spa sequence typing and the BURP (based upon repeat patterns) algorithm.

Author information

1
Institute for Hygiene, University Hospital Münster, Robert-Koch-Str. 41, 48149 Münster, Germany. mellmann@uni-muenster.de

Abstract

We evaluated the BURP (based upon repeat patterns) algorithm, which relies on sequencing of the Staphylococcus aureus protein A gene (spa), for its ability to infer clonal relatedness within a population of 110 wild-type strains. BURP clustering of the resulting 66 spa types was highly concordant with multilocus sequence typing (96.5% concordance) and pulsed-field gel electrophoresis (94.9%).

PMID:
18524961
PMCID:
PMC2519486
DOI:
10.1128/JCM.00071-08
[Indexed for MEDLINE]
Free PMC Article

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