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Cell Stem Cell. 2008 Jun 5;2(6):511-2. doi: 10.1016/j.stem.2008.05.007.

Epithelial-mesenchymal transition and the stem cell phenotype.

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1
Mayo Clinic Cancer Center, Jacksonville, FL 32224, USA. radisky.derek@mayo.edu

Abstract

Epithelial-mesenchymal transition (EMT) is a developmental process in which epithelial cells acquire the motile, migratory properties of mesenchymal cells. In a recent issue of Cell, Mani et al. (2008) show that induction of EMT stimulates cultured breast cells to adopt characteristics of stem cells.

PMID:
18522839
DOI:
10.1016/j.stem.2008.05.007
[Indexed for MEDLINE]
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