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Ann N Y Acad Sci. 2008;1131:75-81. doi: 10.1196/annals.1413.006.

Lymphatic vasculature development: current concepts.

Author information

1
Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital Memphis, TN 38105, USA. guillermo.oliver@stjude.org

Abstract

The recent identification of lymphatic endothelial cell-specific markers and the generation of mouse models harboring mutations in many genes that encode those markers have enabled us to begin to elucidate the developmental steps that go toward establishing the lymphatic vasculature network. Understanding these basic mechanisms of lymphatic development will improve our ability to diagnose, prevent, and ideally treat lymphatic disorders.

PMID:
18519960
DOI:
10.1196/annals.1413.006
[Indexed for MEDLINE]

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