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Acta Ophthalmol. 2009 May;87(3):349-52. doi: 10.1111/j.1755-3768.2008.01208.x. Epub 2008 Jun 28.

Therapeutic efficacy of intravitreal bevacizumab on posterior uveitis complicated by neovascularization.

Author information

1
Department of Ophthalmology, Wake Forest University Eye Centre, Winston Salem, North Carolina 27101, USA. skurup@wfubmc.edu

Abstract

PURPOSE:

To evaluate the therapeutic effect of intravitreal bevacizumab in patients with uveitis-associated choroidal/retinal neovascularization.

METHODS:

Two female patients (40 years, 15 years) with posterior uveitis, (one presumed ocular sarcoidosis, one lupus) were evaluated for neovascularization of the posterior segment. Both patients were given a single dose of 1.25 mg intravitreal bevacizumab.

RESULTS:

Significant anatomical and functional recovery was evident in both patients within a few weeks.

CONCLUSION:

In selected uveitic patients, bevacizumab may be an option for managing neovascularization.

PMID:
18513266
PMCID:
PMC2908182
DOI:
10.1111/j.1755-3768.2008.01208.x
[Indexed for MEDLINE]
Free PMC Article

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