Format

Send to

Choose Destination
See comment in PubMed Commons below
Dev Genes Evol. 2008 Jun;218(6):333-9. doi: 10.1007/s00427-008-0221-4. Epub 2008 May 27.

Expression of homothorax and extradenticle mRNA in the legs of the crustacean Parhyale hawaiensis: evidence for a reversal of gene expression regulation in the pancrustacean lineage.

Author information

1
Department of Developmental Biology, GZMB New Building, Georg-August-University Goettingen, Johann-Friedrich-Blumenbach Institute for Zoology and Anthropology, Justus-von-Liebig-Weg 11, Goettingen, Germany. nprpic@uni-goettingen.de

Abstract

In Drosophila leg development, the extradenticle (exd) gene is expressed ubiquitously and its co-factor homothorax (hth) is restricted to the proximal leg portion. This condition is conserved in other insect species but is reversed in chelicerates and myriapods. As the region of co-expression does not differ in the two groups and transcripts from both are necessary for function, this difference in expression is likely to be functionally neutral. Here, we report the expression patterns of exd and hth in a crustacean, the amphipod shrimp Parhyale hawaiensis. The patterns in P. hawaiensis are similar to the insect patterns, supporting the close relationship between crustaceans and insects in the taxon Tetraconata. However, mRNA expression of exd in P. hawaiensis is weak in the distal leg parts, thus being intermediate between the complete lack of distal exd expression in chelicerates and myriapods and the strong distal exd expression in insects. Our data suggest that the reversal of the gene expression regulation of hth and exd occurred in the pancrustacean lineage.

PMID:
18504609
PMCID:
PMC2668558
DOI:
10.1007/s00427-008-0221-4
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer Icon for PubMed Central
    Loading ...
    Support Center