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Protein Sci. 2008 Aug;17(8):1308-18. doi: 10.1110/ps.036319.108. Epub 2008 May 23.

Kinetic barriers and the role of topology in protein and RNA folding.

Author information

1
University of Chicago, 929 East 57th Street, GCIS W107E, Chicago, IL 60637, USA. trsosnic@uchicago.edu

Abstract

This review compares the folding behavior of proteins and RNAs. Topics covered include the role of topology in the determination of folding rates, major folding events including collapse, properties of denatured states, pathway heterogeneity, and the influence of the mode of initiation on the folding pathway.

PMID:
18502978
PMCID:
PMC2492822
DOI:
10.1110/ps.036319.108
[Indexed for MEDLINE]
Free PMC Article

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