Send to

Choose Destination
See comment in PubMed Commons below
Brain Res Mol Brain Res. 1991 Jan;9(1-2):157-60.

Effects of nerve crush and transection on mRNA levels for nerve growth factor receptor in the rat facial motoneurons.

Author information

Department of Otolaryngology, Osaka University Medical School, Japan.


We found that the level of nerve growth factor receptor (NGF-R) mRNA in facial motoneurons was increased after both facial nerve crushing and transection by means of in situ hybridization histochemistry. The increased level of NGF-R mRNA was maintained for at least 8 weeks after facial nerve transection, while facial nerve crushing caused only a transient increase. Thus, expression of NGF-R mRNA paralleled the axonal regeneration process. In addition, the increase of NGF-R mRNA with crushing was more pronounced than with transection from the 3rd to the 14th day after the insult.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center