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Brain Res Mol Brain Res. 1991 Jan;9(1-2):157-60.

Effects of nerve crush and transection on mRNA levels for nerve growth factor receptor in the rat facial motoneurons.

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1
Department of Otolaryngology, Osaka University Medical School, Japan.

Abstract

We found that the level of nerve growth factor receptor (NGF-R) mRNA in facial motoneurons was increased after both facial nerve crushing and transection by means of in situ hybridization histochemistry. The increased level of NGF-R mRNA was maintained for at least 8 weeks after facial nerve transection, while facial nerve crushing caused only a transient increase. Thus, expression of NGF-R mRNA paralleled the axonal regeneration process. In addition, the increase of NGF-R mRNA with crushing was more pronounced than with transection from the 3rd to the 14th day after the insult.

PMID:
1850072
[Indexed for MEDLINE]
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