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J Cataract Refract Surg. 2008 Jun;34(6):1044-6. doi: 10.1016/j.jcrs.2008.01.030.

Descemet-stripping endothelial keratoplasty: improvement in vision following replacement of a healthy endothelial graft.

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Spectrum Eye Physicians, San Jose, California 95129, USA.


We describe a case of endothelial graft exchange in a patient who had inadequate vision without a clinically identifiable cause following Descemet-stripping endothelial keratoplasty (DSEK). The initial DSEK was performed with a hand-dissected donor, and the replacement graft was prepared with an automated microkeratome. The best spectacle-corrected visual acuity (BSCVA) improved from 20/50 before replacement to 20/25 after replacement. Although DSEK provides rapid recovery of excellent vision, few patients achieve a BSCVA of 20/20. Some have substandard vision with no clinically identifiable cause. This case demonstrates that replacing a hand-prepared graft with an automated microkeratome-prepared graft may improve vision in patients with no identifiable cause for visual loss.

[Indexed for MEDLINE]

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