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Immunity. 2008 May;28(5):596-8. doi: 10.1016/j.immuni.2008.04.012.

Along came a spider: AID escapes a microRNA web.

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1
Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. sdesider@jhmi.edu

Abstract

In this issue of Immunity, Teng et al. (2008) and Dorsett et al. (2008) report that activation-induced cytidine deaminase in B cells is repressed by microRNA-155. Relief of repression is associated with defective affinity maturation and increased Myc-Igh translocations.

PMID:
18482561
DOI:
10.1016/j.immuni.2008.04.012
[Indexed for MEDLINE]
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