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Acta Derm Venereol. 2008;88(3):247-51. doi: 10.2340/00015555-0434.

Treatment of chronic urticaria with narrowband ultraviolet B phototherapy: a randomized controlled trial.

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1
Department of Dermatology, Meram Medical Faculty, Selcuk University, Konya, Turkey. burhanengin2000@yahoo.com

Abstract

Data regarding narrowband ultraviolet B (NB-UVB) phototherapy in patients with chronic urticaria is limited. The aim of this open, controlled study was to determine whether NB-UVB is effective in treating urticaria in combination with antihistamin. A total of 81 patients with chronic urticaria were recruited, 48 of whom were randomized into the NB-UVB plus antihistamine group. The control group (n = 33) received only antihistamine. Patients were assessed using the urticaria activity score and a visual analogue score (VAS). The 2 groups were evaluated at the same time-points: at treatment sessions 10 and 20 and at follow-up 3 months post-treatment. The reduction in urticaria activity score and VAS was statistically significant (p < 0.05 for both groups). When comparing the groups, the mean urticaria activity score was significantly lower in the NB-UVB group at session 10 (22.6 vs. 27.3) and session 20 (17.4 vs. 20.7). Statistically significant differences were also noted in VAS between the 2 groups (p < 0.01) at 3 months post-treatment. We conclude that NB-UVB may be an effective complementary treatment for patients with chronic urticaria.

PMID:
18480923
DOI:
10.2340/00015555-0434
[Indexed for MEDLINE]
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