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J Postgrad Med. 2008 Apr-Jun;54(2):102-5.

Fournier's gangrene: evaluation of 68 patients and analysis of prognostic variables.

Author information

1
General Surgery Clinic, Ataturk Training and Research Hospital, Izmir, Turkey. drhru@mynet.com

Abstract

CONTEXT:

Fournier's gangrene (FG) is a rapidly progressing acute gangrenous infection of the anorectal and urogenital area.

AIMS:

The objectives of this study were to investigate patients with FG and to determine risk factors that affect mortality.

SETTINGS AND DESIGN:

Retrospective clinical study.

MATERIALS AND METHODS:

Clinical presentations and outcomes of surgical treatments were evaluated in 68 patients with FG.

STATISTICAL ANALYSIS USED:

Chi-square, Student's t -test, and logistic regression test.

RESULTS:

Mean age of patients was 54 and female-to-male ratio was 9:59. Among the predisposing factors, diabetes mellitus (DM) was the most common ( n =24, 35.3%), and sepsis on admission was detected in 31 (45.6%) and 15 (22.1%) patients, respectively. Seven (10.3%) patients died. Using logistic regression test, Fournier's Gangrene Severity Index (FGSI)> 9, DM and sepsis on admission were found as prognostic factors.

CONCLUSIONS:

FG has a high mortality rate, especially in patients with DM and sepsis. An FGSI value> 9 indicates high mortality rate.

Comment in

PMID:
18480525
DOI:
10.4103/0022-3859.40775
[Indexed for MEDLINE]
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