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Biotechniques. 2008 Apr;44(5):701-4. doi: 10.2144/000112796.

Kits and their unique role in molecular biology: a brief retrospective.

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Affomix Corporation, New Haven, CT 06511, USA.


Since their initial development nearly 20 years ago, molecular biology kits have evolved from simple protocols and reagents for cloning of DNA to the more recent complex reagent sets that enable whole genomic sequencing. Initially met with resistance by some who felt that using them deprived researchers of the basic knowledge of how to create reagents, molecular biology kits have taken on an important role in the biological sciences. In this article we describe kit development, why kits have succeeded in molecular biology, and how they have paved the way for the more recent widespread use of core facilities.

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