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Antimicrob Agents Chemother. 2008 Jul;52(7):2667-72. doi: 10.1128/AAC.01516-07. Epub 2008 May 5.

Molecular characterization of Enterococcus faecalis N06-0364 with low-level vancomycin resistance harboring a novel D-Ala-D-Ser gene cluster, vanL.

Author information

1
National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.

Abstract

Enterococcus faecalis N06-0364, exhibiting a vancomycin MIC of 8 microg/ml, was found to harbor a novel D-Ala-D-Ser gene cluster, designated vanL. The vanL gene cluster was similar in organization to the vanC operon, but the VanT serine racemase was encoded by two separate genes, vanTm(L) (membrane binding) and vanTr(L) (racemase).

PMID:
18458129
PMCID:
PMC2443935
DOI:
10.1128/AAC.01516-07
[Indexed for MEDLINE]
Free PMC Article

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