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Bioinformatics. 2008 Jul 1;24(13):1556-8. doi: 10.1093/bioinformatics/btn217. Epub 2008 May 3.

DAnTE: a statistical tool for quantitative analysis of -omics data.

Author information

1
Pacific Northwest National Laboratory, Richland, WA 99352, USA.

Abstract

Data Analysis Tool Extension (DAnTE) is a statistical tool designed to address challenges associated with quantitative bottom-up, shotgun proteomics data. This tool has also been demonstrated for microarray data and can easily be extended to other high-throughput data types. DAnTE features selected normalization methods, missing value imputation algorithms, peptide-to-protein rollup methods, an extensive array of plotting functions and a comprehensive hypothesis-testing scheme that can handle unbalanced data and random effects. The graphical user interface (GUI) is designed to be very intuitive and user friendly.

AVAILABILITY:

DAnTE may be downloaded free of charge at http://omics.pnl.gov/software/.

SUPPLEMENTARY INFORMATION:

An example dataset with instructions on how to perform a series of analysis steps is available at http://omics.pnl.gov/software/

PMID:
18453552
PMCID:
PMC2692489
DOI:
10.1093/bioinformatics/btn217
[Indexed for MEDLINE]
Free PMC Article

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