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J Med Case Rep. 2008 Apr 30;2:136. doi: 10.1186/1752-1947-2-136.

Radiation-induced morphea of the breast: a case report.

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Cancer Centre, Queen Elizabeth Hospital, University Hospital Birmingham NHS Trust, Edgbaston, Birmingham, UK.


Radiation-induced morphea (RIM) of the breast is a rare complication of radiotherapy. It is disfiguring, painful and defeats the purpose of achieving a good cosmesis in breast-conservation surgery. This report describes a severe case of RIM in a breast cancer patient together with photographic illustrations of the serial changes over time and histopathology slides. A review of the literature is provided.

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