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Brief Bioinform. 2008 Jul;9(4):326-32. doi: 10.1093/bib/bbn016. Epub 2008 Apr 24.

The TRANSFAC project as an example of framework technology that supports the analysis of genomic regulation.

Author information

1
Department of Bioinformatics, Medical School, University of Göttingen, Goldschmidtstr. 1, D-37077 Göttingen, Germany. e.wingender@med.uni-goettingen.de

Abstract

Since its beginning as a data collection more than 20 years ago, the TRANSFAC project underwent an evolution to become the basis for a complex platform for the description and analysis of gene regulatory events and networks. In the following, I describe what the original concepts were, what their present status is and how they may be expected to contribute to future system biology approaches.

PMID:
18436575
DOI:
10.1093/bib/bbn016
[Indexed for MEDLINE]

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