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Expert Opin Drug Metab Toxicol. 2008 Apr;4(4):507-11. doi: 10.1517/17425255.4.4.507 .

Ketorolac tromethamine 0.4% as a treatment for allergic conjuctivitis.

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1
Florida Eye Microsurgical Institute, 1717 W Woolbright Road, Boynton Beach, FL 33426, USA. BDSCH77@aol.com

Abstract

BACKGROUND:

Acular LS (ketorolac tromethamine 0.4%) ophthalmic solution, a reformulation of the original Acular (ketorolac tromethamine 0.5%), is indicated for the reduction of ocular pain and burning/stinging following corneal refractive surgery.

OBJECTIVE:

This manuscript will review the off-label application of this topical NSAID medication as a treatment for allergic conjunctivitis.

METHODS:

An extensive MedLine search was undertaken to evaluate data on the use of ketorolac for allergic conjunctivitis. Data on both human and animal data were reviewed.

RESULTS/CONCLUSIONS:

Studies have demonstrated that ketorolac 0.4% has equivalent efficacy to ketorolac 0.5%. Several studies have demonstrated that ketorolac effectively treats allergic conjunctivitis. Ketorolac 0.4% is effective when used as either monotherapy or as adjunct therapy to steroids.

PMID:
18433352
DOI:
10.1517/17425255.4.4.507
[Indexed for MEDLINE]
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