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Nat Rev Mol Cell Biol. 2008 Jun;9(6):431-6. doi: 10.1038/nrm2399. Epub 2008 Apr 23.

Membrane nanotubes: dynamic long-distance connections between animal cells.

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  • 1Division of Cell and Molecular Biology, Sir Alexander Fleming Building, Imperial College, London, SW7 2AZ, UK. d.davis@imperial.ac.uk

Abstract

Membrane nanotubes are transient long-distance connections between cells that can facilitate intercellular communication (for example, by trafficking vesicles or transmitting calcium-mediated signals), but they can also contribute to pathologies (for example, by directing the spread of viruses). Recent data have revealed considerable heterogeneity in their structures, processes of formation and functional properties, in part dependent on the cell types involved. Despite recent progress in this young research field, further research is sorely needed.

PMID:
18431401
DOI:
10.1038/nrm2399
[PubMed - indexed for MEDLINE]
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