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Curr Protoc Protein Sci. 2001 Nov;Chapter 21:Unit 21.3. doi: 10.1002/0471140864.ps2103s25.

Overview of pepsin-like aspartic peptidases.

Author information

1
University of Florida College of Medicine, Gainesville, Florida, USA.

Abstract

The aspartic peptidase family of enzymes has been implicated in a variety of disease states, from stomach ulcers, to breast cancer, and even Alzheimer's Disease. This unit describes the major characteristics of the aspartic peptidases, including mechanism of action, subcellular and tissue localization, and biological substrate specificity.

PMID:
18429164
DOI:
10.1002/0471140864.ps2103s25
[Indexed for MEDLINE]

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