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Curr Protoc Bioinformatics. 2006 Mar;Chapter 2:Unit 2.10. doi: 10.1002/0471250953.bi0210s13.

Using the Structure-function Linkage Database to characterize functional domains in enzymes.

Author information

1
University of California, San Francisco, San Francisco, California, USA.

Abstract

The Structure-Function Linkage Database (SFLD; http://sfld.rbvi.ucsf.edu/) is a Web-accessible database designed to link enzyme sequence, structure, and functional information. This unit describes the protocols by which a user may query the database to predict the function of newly sequenced enzymes and to correct misannotated functional assignments for enzymes currently in public databases. It is especially useful in helping a user discriminate functional capabilities of a sequence that is only distantly related to characterized sequences in publicly available databases.

PMID:
18428763
DOI:
10.1002/0471250953.bi0210s13
[Indexed for MEDLINE]

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