Format

Send to

Choose Destination
Curr Opin Pulm Med. 2008 May;14(3):248-53. doi: 10.1097/MCP.0b013e3282f7646f.

Recent antiviral strategies against human coronavirus-related respiratory illnesses.

Author information

1
Microbiology Department, Faculty of Biochemistry Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.

Abstract

PURPOSE OF REVIEW:

The main purpose of this review is to summarize the current research (2006-2007) concerning the development of novel anticoronaviral strategies and compounds.

RECENT FINDINGS:

Recent research led to the identification of several novel agents inhibiting coronaviral replication. The most promising compounds include carbohydrate-binding agents, neutralizing antibodies and drugs targeting a coronaviral envelope protein.

SUMMARY:

Although initial outbreaks of coronavirus that causes severe acute respiratory syndrome (SARS-CoV) were controlled by public health measures, the development of vaccines and antiviral agents for SARS-CoV is essential for improving control and treatment of future outbreaks. Four years after the SARS-CoV epidemic, several compounds with an anticoronaviral activity have been identified.

PMID:
18427249
DOI:
10.1097/MCP.0b013e3282f7646f
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wolters Kluwer
Loading ...
Support Center