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Cell Mol Life Sci. 2008 Jun;65(11):1626-30. doi: 10.1007/s00018-008-7536-1.

Considerations on temperature, longevity and aging.

Author information

1
Molecular and Integrative Neurosciences Department, The Harold Dorris Neurological Research Institute, The Scripps Research Institute, La Jolla, CA 92037, USA. bconti@scripps.edu

Abstract

A modest reduction in body temperature prolongs longevity and may retard aging in both poikilotherm and homeotherm animals. Some of the possible mechanisms mediating these effects are considered here with respect to major aging models and theories.

PMID:
18425417
PMCID:
PMC2574693
DOI:
10.1007/s00018-008-7536-1
[Indexed for MEDLINE]
Free PMC Article

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