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Gastrointest Endosc. 2008 Sep;68(3):440-6. doi: 10.1016/j.gie.2008.02.009. Epub 2008 Apr 18.

The beneficial effects of argon plasma coagulation in the management of different types of gastric vascular ectasia lesions in patients admitted for GI hemorrhage.

Author information

1
Endoscopy Unit, Institut de Malalties Digestives i Metabòliques, Hospital Clinic, University of Barcelona, Catalonia, Spain.

Abstract

BACKGROUND:

Despite different forms of treatment, few studies have been performed on the outcome and prognosis of patients admitted to the hospital because of gastric vascular ectasia (GVE) and upper-GI bleeding (UGIB). There is also little knowledge on the efficacy of argon plasma coagulation (APC) in different subgroups of GVE lesions.

OBJECTIVE:

This study was designed to evaluate the efficacy of APC in patients admitted to the hospital with UGIB because of GVE.

DESIGN:

Prospective evaluation of consecutive cases of UGIB because of GVE.

SETTING:

Tertiary and university-affiliated hospital.

PATIENTS AND INTERVENTIONS:

Twenty-nine patients were included and divided into 3 subgroups: focal vascular ectasia lesions (FVE) (n = 10), portal hypertensive gastropathy (PHG) (n = 11), and gastric antral vascular ectasia (GAVE) (n = 8). Patients were followed at 3 months and every 6 months thereafter during a mean of 23.1 months (range 18-37 months). All patients received intensive APC treatment that was repeated, depending on the endoscopic appearance or clinical evaluation.

RESULTS:

The overall success of APC treatment was 86%, with only one recurrence of UGIB during the follow-up period. The number of APC sessions was 1.2, 2.2, and 2.3, in each subgroup (not significant), with a total number of sessions of 1.9 +/- 1.3. Treatment success was 90% in the FVE group, 81% in the PHG group, and 87.5% in the GAVE group (NS). The rise in hematocrit from baseline values in the overall group and in each subgroup was significant (P > .01).

LIMITATIONS:

A single-center study and small sample.

CONCLUSIONS:

Endoscopic thermal ablation with APC is effective in managing UGIB and in reducing transfusion requirements in patients admitted for GI hemorrhage because of different endoscopic types of GVE.

PMID:
18423466
DOI:
10.1016/j.gie.2008.02.009
[Indexed for MEDLINE]

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