Format

Send to

Choose Destination
See comment in PubMed Commons below
Arch Neurol. 2008 Apr;65(4):452-6. doi: 10.1001/archneur.65.4.452.

The changing face of neural stem cell therapy in neurologic diseases.

Author information

1
Department of Neurology, Agnes Ginges Center for Human Neurogenetics, Hadassah-Hebrew University Medical Center, Ein-Kerem, Jerusalem, Israel.

Abstract

New insights into the biology of neural stem cells (NSCs) have raised expectations for their use in the treatment of neurologic diseases. Originally, NSC transplantation was proposed as a means of replacing cells in central nervous system diseases that result in cell loss. However, recent data regarding their beneficial effects in various animal models of neurologic diseases indicate that transplanted NSCs may also attenuate deleterious inflammation, protect the central nervous system from degeneration, and enhance endogenous recovery processes. Herein, we review recent developments and future prospects of NSC therapy in neurologic diseases.

PMID:
18413466
DOI:
10.1001/archneur.65.4.452
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems
    Loading ...
    Support Center