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Am J Med Genet C Semin Med Genet. 2008 May 15;148C(2):127-32. doi: 10.1002/ajmg.c.30169.

Genetics of post-traumatic stress disorder: informing clinical conceptualizations and promoting future research.

Author information

1
Brown Medical School and Bradley/ Hasbro Children's Research Center, USA.

Abstract

The purpose of this article is to provide an overview of genetic research involving post-traumatic stress disorder (PTSD). First, we summarize evidence for genetic influences on PTSD from family investigations. Second, we discuss the distinct contributions to our understanding of the genetics of PTSD permitted by twin studies. Finally, we summarize findings from molecular genetic studies, which have the potential to inform our understanding of underlying biological mechanisms for the development of PTSD.

PMID:
18412098
PMCID:
PMC2680188
DOI:
10.1002/ajmg.c.30169
[Indexed for MEDLINE]
Free PMC Article

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