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BJOG. 2008 May;115(6):726-31. doi: 10.1111/j.1471-0528.2008.01705.x.

The risk of unexplained antepartum stillbirth in second pregnancies following caesarean section in the first pregnancy.

Author information

1
Department of Obstetrics and Gynecology, University of Calgary, Foothills Hospital, Calgary, Alberta, Canada. stephen.wood@calgaryhealthregion.ca

Abstract

OBJECTIVE:

To determine if a previous caesarean section increases the risk of unexplained antepartum stillbirth in second pregnancies.

STUDY DESIGN:

Retrospective cohort study.

SETTING:

Large Canadian perinatal database.

POPULATION:

158 502 second births.

METHODS:

Data were obtained from a large perinatal database, which supplied data on demographics, pregnancy complications, maternal medical conditions, previous caesarean section and pregnancy outcomes.

MAIN OUTCOME MEASURES:

Total and unexplained stillbirth.

RESULTS:

The antepartum stillbirth rate was 3.0/1000 in the previous caesarean section group compared with 2.7/1000 in the previous vaginal delivery group (P= 0.46). Multivariate logistic regression modelling, including terms for maternal age (polynomial), weight >91 kg, smoking during pregnancy, pre-pregnancy hypertension and diabetes, did not document an association between previous caesarean section and unexplained antepartum stillbirth (OR 1.27, 95% CI 0.92-1.77).

CONCLUSION:

Caesarean section in the first birth does not increase the risk of unexplained antepartum stillbirth in second pregnancies.

[Indexed for MEDLINE]
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