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Cardiol Clin. 2008 May;26(2):267-75, vii. doi: 10.1016/j.ccl.2007.12.011.

Reducing the risk for stroke in patients who have atrial fibrillation.

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1
Department of Internal Medicine, 1 University of New Mexico, MSC10 5550, Albuquerque, NM 87131, USA. davgarcia@salud.unm.edu

Abstract

Warfarin is highly effective at reducing the risk of stroke in AF. The benefit of oral anticoagulant therapy strongly outweighs the risk in most patients who have AF. More data are needed to define the overall risk-to-benefit ratio better for patients aged 80 years and older. Because a significant proportion of elderly individuals may not be optimal candidates for anticoagulant therapy, we must continue to evaluate alternative stroke prevention strategies while redoubling our efforts to understand the mechanisms underlying AF and thrombogenesis.

PMID:
18406999
DOI:
10.1016/j.ccl.2007.12.011
[Indexed for MEDLINE]
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