Format

Send to

Choose Destination
See comment in PubMed Commons below
J Neurosci. 2008 Apr 9;28(15):4078-87. doi: 10.1523/JNEUROSCI.5338-07.2008.

Functional asymmetries in visual pathways carrying S-cone signals in macaque.

Author information

1
Center for Neural Science, New York University, New York, New York 10003, USA. ctailby@unimelb.edu.au

Abstract

In the lateral geniculate nucleus of macaque, we recorded from neurons with substantial input from S-cones and found that, on several important dimensions, the properties of neurons that receive inhibitory input from S-cones ("S-") are quite unlike those of neurons that receive excitatory input from S-cones ("S+"). First, the organization of chromatic inputs differs substantially: in S+ cells, S-cone signals were usually opposed by those of L- and M-cones; in S- cells, signals from L-cones were usually opposed to those of S- and M-cones. Second, to pure S-cone modulation, S+ cells are twice as sensitive as S- cells, but S- cells were much more susceptible to contrast adaptation. Third, in S- cells but not S+ cells, the spatial frequency resolution for achromatic modulation was often greater, the tuning curve and more bandpass, than that for S-cone modulation. Along the dimensions on which we measured, the properties of the S+ cells were relatively tightly clustered, suggesting a homogenous class. Although the chromatic properties of S- cells are heterogeneous, the distribution of their tuning along other stimulus dimensions does not suggest multiple subtypes.

PMID:
18400907
PMCID:
PMC2602833
DOI:
10.1523/JNEUROSCI.5338-07.2008
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center