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Cell Stem Cell. 2008 Apr 10;2(4):302-4. doi: 10.1016/j.stem.2008.03.017.

Hematopoietic stem cells in transit--where's the niche?

Author information

1
Department of Molecular, Cellular, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Abstract

In this issue of Cell Stem Cell, Min et al. (2008) identify Egr1 as a novel hematopoietic stem cell (HSC) transcription factor that regulates proliferation and mobilization of these cells. An improved understanding of Egr1 targets may lead to better strategies to expand populations of HSCs ex vivo for therapeutic applications.

PMID:
18397748
DOI:
10.1016/j.stem.2008.03.017
[Indexed for MEDLINE]
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