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Mol Immunol. 2008 Jun;45(11):3023-4. doi: 10.1016/j.molimm.2008.02.015. Epub 2008 Apr 18.

Searching for autoimmunity in "antibiotic-refractory" Lyme arthritis.

Abstract

In two recent articles published in Molecular Immunology, Steere and colleagues continue their search for an autoimmune mechanism of arthritis in patients who have failed short-course antibiotic therapy for Borrelia burgdorferi, the spirochetal agent of Lyme disease. As in previous attempts, the authors fail to elucidate a molecular mimicry mechanism for the putative autoimmune process, leading to the conclusion that there is no credible scientific evidence for a post-infectious autoimmune mechanism of arthritis in chronic Lyme disease.

PMID:
18395260
DOI:
10.1016/j.molimm.2008.02.015
[Indexed for MEDLINE]

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