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Cell. 2008 Apr 4;133(1):25-6. doi: 10.1016/j.cell.2008.03.015.

Sorting out small RNAs.

Author information

1
School of Biological Sciences and National Creative Research Initiatives Center, Seoul National University, Seoul, 151-742, Korea. narrykim@snu.ac.kr

Abstract

Small RNAs carry out their functions by guiding Argonaute (AGO) proteins to their targets. Diverse types of small RNAs and multiple AGO proteins exist in most eukaryotic species, but how small RNAs are sorted into specific AGO complexes remains unclear. Two papers in this issue (Mi et al., 2008; Montgomery et al., 2008) now reveal the importance of the 5' terminal nucleotide of the small RNA in the sorting process in Arabidopsis.

PMID:
18394983
DOI:
10.1016/j.cell.2008.03.015
[Indexed for MEDLINE]
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