Format

Send to

Choose Destination
Acta Paediatr. 2008 May;97(5):568-73. doi: 10.1111/j.1651-2227.2008.00738.x.

Preterm infants of educated mothers have better outcome.

Author information

1
Department of Pediatrics, Chi Mei Medical Center; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan. lanwan@ms67.url.com.tw

Abstract

AIM:

To determine the developmental trajectories of very-low-birthweight (VLBW) infants during the first 2 years of life, and investigate the most contributory predictors of diverse trajectories.

METHODS:

This prospective cohort study enrolled 887 VLBW infants from January 1999 to December 2002 with regular follow-up at corrected age of 6, 12, 18 and 24 months. Sociodemographic and medical data were collected, and the outcome measures consisted of neurological assessment and the Bayley Scales of Infant Development-II.

RESULTS:

Five trajectories of cognitive development based on the mental developmental indices from the age of 6 to 24 months were determined, including average-stable (group A, 20.1%), average-decline to borderline delay (group B, 34%), borderline delay-catch-up to average (group C, 20.2%), borderline delay-decline to significant delay (group D, 17.2%) and significant delay-stable (group E, 8.5%). Using group A as the reference category, we determined 6-month neurological status and maternal education as the most significant predictors for various trajectories (p < 0.01). Infants with transient or definite neurological abnormality and/or low maternal education had higher odds of displaying the disadvantageous trajectories (group B, D and E; odds ratios, 1.79-46.4).

CONCLUSION:

VLBW infants with neurological abnormalities and/or low maternal education had high risk of developmental decline and might benefit from early intervention.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center