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Support Care Cancer. 2008 Aug;16(8):879-89. doi: 10.1007/s00520-008-0418-0. Epub 2008 Apr 8.

Impact of skeletal complications on patients' quality of life, mobility, and functional independence.

Author information

1
Instituto de Medicina Molecular-Lisboa, Servico de Oncologia, Hospital de Santa Maria, Av Professor Egaz Moniz, Lisbon, 1649-039, Portugal. luiscosta.p@netcabo.pt

Erratum in

  • Support Care Cancer. 2008 Oct;16(10):1201.

Abstract

INTRODUCTION:

Skeletal-related events (SREs) from malignant bone disease cause considerable morbidity and can dramatically reduce patients' quality of life.

DISCUSSION:

Pathologic fractures often require surgical intervention and palliative radiotherapy. Thus, patients suffer impaired mobility, loss of functional independence, and diminished health-related quality of life (HRQOL). Bisphosphonates can delay the onset and reduce the incidence of SREs and have become the standard of care for the treatment of malignant bone disease; however, minimal information on the effects of bisphosphonate treatment on HRQOL is available. Targeted HRQOL assessments for patients with malignant bone disease are currently under development and are discussed herein.

PMID:
18392862
DOI:
10.1007/s00520-008-0418-0
[Indexed for MEDLINE]

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