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Cell Stem Cell. 2007 Aug 16;1(2):131-2. doi: 10.1016/j.stem.2007.07.018.

Short-circuiting epiblast development.

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  • 1The Stowers Medical Institute, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA.


Although human and mouse embryonic stem cells share many characteristics, their behaviors are not identical. Two recent papers describe the derivation of stem cell lines from mouse epiblast that may provide an explanation for the unique character of human embryonic stem cells.

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