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BMC Genomics. 2008 Mar 18;9:130. doi: 10.1186/1471-2164-9-130.

An anatomy ontology to represent biological knowledge in Dictyostelium discoideum.

Author information

1
dictyBase, Northwestern University, Center for Genetic Medicine, 676 N, St, Clair, Chicago, IL 60611, USA. pgaudet@northwestern.edu

Abstract

BACKGROUND:

Dictyostelium discoideum is a model system for studying many important physiological processes including chemotaxis, phagocytosis, and signal transduction. The recent sequencing of the genome has revealed the presence of over 12,500 protein-coding genes. The model organism database dictyBase hosts the genome sequence as well as a large amount of manually curated information.

RESULTS:

We present here an anatomy ontology for Dictyostelium based upon the life cycle of the organism.

CONCLUSION:

Anatomy ontologies are necessary to annotate species-specific events such as phenotypes, and the Dictyostelium anatomy ontology provides an essential tool for curation of the Dictyostelium genome.

PMID:
18366659
PMCID:
PMC2323390
DOI:
10.1186/1471-2164-9-130
[Indexed for MEDLINE]
Free PMC Article

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