Format

Send to

Choose Destination
See comment in PubMed Commons below
Biochim Biophys Acta. 2008 Nov;1779(11):720-4. doi: 10.1016/j.bbagrm.2008.02.009. Epub 2008 Mar 4.

Diverse small RNA-directed silencing pathways in plants.

Author information

1
Department of Biological Sciences, Texas Tech University, P. O. Box 43131, Lubbock, Texas 79409, USA. zhixin.xie@ttu.edu

Abstract

Small silencing RNAs of 21- to 24-nucleotide (nt) in length are essential regulatory components expressed in most eukaryotic organisms. These regulatory small RNAs are produced through pathways that involve several evolutionarily conserved protein families, including DICER (DCR) or DICER-LIKE (DCL), ARGONAUTE (AGO), and RNA-DEPENDENT RNA POLYMERASE (RDR). Plants possess multiple functional DCL, RDR, and AGO proteins. Genetic analyses in the model plant Arabidopsis thaliana have revealed multiple small RNA pathways, each utilizing a distinct set of RNA silencing factors. In this short review, mainly based on the work done on A. thaliana, we give a brief overview on the multiple small RNA-directed silencing pathways in plants, which includes the biogenesis and function of microRNAs (miRNAs), trans-acting siRNAs (ta-siRNAs), natural cis-antisense transcripts-associated siRNAs (nat-siRNAs), and heterochromatic siRNAs.

PMID:
18358247
DOI:
10.1016/j.bbagrm.2008.02.009
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center