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Eye (Lond). 2009 Mar;23(3):559-60. doi: 10.1038/eye.2008.65. Epub 2008 Mar 21.

In vitro antibiotic susceptibility of preoperative normal conjunctival bacteria.

Author information

1
Department of Ophthalmology, School of Medicine, Stanford University, Stanford, CA 94305, USA. cta@ stanford.edu

Abstract

PURPOSE:

To determine the antibiotic susceptibility of preoperative conjunctival bacterial flora.

METHODS:

Antibiotic susceptibility of conjunctival bacterial strains isolated from 142 patients undergoing intraocular surgery was determined using the Kirby-Bauer disc diffusion technique. chi(2) statistical analysis was performed.

RESULTS:

Among the 116 bacteria isolated, 95 (82%) were coagulase-negative staphylococci (CNS). Most (>75%) of them were susceptible to vancomycin, minocycline, aminoglycosides, gatifloxacin, levofloxacin, and moxifloxacin. Approximately one-half of CNS was resistant to erythromycin and azithromycin. Over 90% of streptococci were susceptible to levofloxacin, moxifloxacin, and gatifloxacin.

RESULTS:

Fluoroquinolones, specifically gatifloxacin, levofloxacin, and moxifloxacin continue to provide broad-spectrum coverage against common conjunctival bacterial flora.

PMID:
18356928
DOI:
10.1038/eye.2008.65
[Indexed for MEDLINE]

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