Format

Send to

Choose Destination
See comment in PubMed Commons below
Am J Obstet Gynecol. 2008 Aug;199(2):131.e1-4. doi: 10.1016/j.ajog.2008.02.013. Epub 2008 Mar 20.

A comparison of speculum and nonspeculum collection of cervicovaginal specimens for fetal fibronectin testing.

Author information

1
Department of Obstetrics and Gynecology, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

Abstract

OBJECTIVE:

Current recommendations include the use of a vaginal speculum for fetal fibronectin specimen collection. This article evaluates the equivalency of nonspeculum methods for collecting fetal fibronectin specimens.

STUDY DESIGN:

Two separate prospective studies of patients more than 22 weeks' gestation were performed at 2 institutions with similar hypotheses and methods. Two sequential specimens were collected on each patient: 1 with speculum and 1 with the nonspeculum method. The order of collection was reversed or randomized in both studies. Two alternative nonspeculum collection methods are described.

RESULTS:

The 2 study sample sizes were 169 and 31. Comparison of the fetal fibronectin test results between the speculum and nonspeculum methods demonstrated greater than 95% agreement with an intraclass Kappa coefficient greater than 0.85 in both studies. The order of collection did not result in significantly different fetal fibronectin averages.

CONCLUSION:

These studies demonstrate that there is excellent agreement between fetal fibronectin results obtained by speculum and nonspeculum collection methods.

PMID:
18355785
DOI:
10.1016/j.ajog.2008.02.013
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center