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Fertil Steril. 2009 Apr;91(4 Suppl):1299-302. doi: 10.1016/j.fertnstert.2008.01.050. Epub 2008 Mar 18.

Ovarian follicular volume and follicular surface area are better indicators of follicular growth and maturation, respectively, than is follicular diameter.

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1
Florida Institute for Reproductive Sciences and Technologies, Weston, Florida 33326-3257, USA.

Abstract

Because ovarian follicular growth occurs in three dimensions, and because follicular maturation (increased E(2)) is a result of an increase in the three-dimensional follicular surface area where testosterone (E(2) precursor)-producing theca interna cells are located, the three-dimensional follicular volume and the three-dimensional follicular surface area describe the three-dimensional follicular growth and maturation, respectively, more accurately than does the two-dimensional follicular diameter alone. Therefore, we present a mathematical model that describes the relationship of the two-dimensional follicular diameter, the three-dimensional follicular volume, and the three-dimensional follicular surface area to the three-dimensional follicular growth and maturation.

[Indexed for MEDLINE]

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