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Immunity. 2008 Mar;28(3):300-1. doi: 10.1016/j.immuni.2008.02.010.

Living in context with the survival factor BAFF.

Author information

1
Department of Pathology and Laboratory Medicine, 284 John Morgan Building, University of Pennsylvania School of Medicine, 36th and Hamilton Walk, Philadelphia, PA 19104-6082, USA. cancro@mail.med.upenn.edu

Abstract

In this issue, Gardham et al. (2008) show that BAFF, a tumor necrosis factor (TNF) family member, promotes B cell survival by hindering interactions between TNF-receptor-associated factors, blocking their negative regulation of nonclassical NF-kappaB activity.

PMID:
18342003
DOI:
10.1016/j.immuni.2008.02.010
[Indexed for MEDLINE]
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