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Fertil Steril. 2009 Mar;91(3):946-8. doi: 10.1016/j.fertnstert.2007.12.009. Epub 2008 Mar 12.

Autoimmune response to Chlamydia trachomatis infection and in vitro fertilization outcome.

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Dipartimento di Scienze Ginecologiche, Perinatologia e Puericultura, Policlinico Umberto Io, Università di Roma La Sapienza, Rome, Italy.


This observational study was conducted in 235 patients undergoing IVF who had a cervical swab positive for Chlamydia trachomatis and who underwent antibiotic treatment until a negative cervical swab before IVF attempt. After oocyte retrieval, follicular fluids of 109 patients out of 228 still showed the presence of IgA antichlamydia antibodies and a significantly lower pregnancy and implantation rate; therefore we conclude that patients should undergo IVF procedure after serum antichlamydia IgA tests negative.

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