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Bioorg Med Chem. 2008 Apr 15;16(8):4203-21. doi: 10.1016/j.bmc.2008.02.069. Epub 2008 Feb 26.

Tetramic and tetronic acids: an update on new derivatives and biological aspects.

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1
Organic Chemistry Laboratory, University of Bayreuth, Bayreuth, Germany. Rainer.Schobert@uni-bayreuth.de

Abstract

Significant developments in the isolation of tetramic acids and tetronic acids, in the elucidation of their biosyntheses and their biological activities and in laboratory syntheses are reviewed with a focus on those derivatives with medicinal and pharmacological relevance. Important new members of the title compound families isolated since the year 2000 are covered as well as new biological aspects of some earlier congeners.

PMID:
18334299
DOI:
10.1016/j.bmc.2008.02.069
[Indexed for MEDLINE]
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