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Antimicrob Agents Chemother. 2008 May;52(5):1855-8. doi: 10.1128/AAC.01567-07. Epub 2008 Mar 10.

Efficacy of benzoxazinorifamycins in a mouse model of Chlamydia pneumoniae lung infection.

Author information

1
Department of Pathobiology, University of Washington, Seattle, Washington 98195, USA.

Abstract

The efficacy of rifalazil and other benzoxazinorifamycins was tested in a mouse model of lung infection against Chlamydia pneumoniae. Rifalazil and six related new chemical entities all showed efficacy after one dose per day for 3 days at either 3 or 1 mg/kg of body weight.

PMID:
18332169
PMCID:
PMC2346613
DOI:
10.1128/AAC.01567-07
[Indexed for MEDLINE]
Free PMC Article

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