Format

Send to

Choose Destination
Drug Alcohol Depend. 2008 May 1;95(1-2):107-14. doi: 10.1016/j.drugalcdep.2007.12.017. Epub 2008 Mar 6.

Transitions to regular smoking and to nicotine dependence in women using cannabis.

Author information

1
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA. arpana@wustl.edu

Abstract

BACKGROUND:

While there is substantial support in the literature for an increased prevalence of cannabis use in cigarette smokers, emerging studies allude to the possibility that cannabis users may, in turn, be at significantly elevated risk for rapid transitions in their cigarette smoking trajectories. If there is evidence in its favor, the increased rates of cigarette smoking in cannabis users may prove to be the most significant public health problem associated with cannabis use.

METHODS:

In a sample of 3787 female twins (age range 18-29 years), we examined, using discrete-time survival analyses, whether women who reported cannabis use were at increased risk for regular cigarette smoking and progression to nicotine dependence.

RESULTS:

After controlling for a large number of potential covariates, we found that women who used cannabis were at 4.4 and 2.8 increased hazards for transitioning from initiation to regular smoking and from regular smoking to nicotine dependence, respectively.

CONCLUSIONS:

Cannabis use is associated with transitions to more involved stages of cigarette smoking in women. This is a source of public health concern, first due to the high mortality associated with cigarette smoking and second, due to the high prevalence of cannabis use in the general population.

PMID:
18325694
PMCID:
PMC2336108
DOI:
10.1016/j.drugalcdep.2007.12.017
[Indexed for MEDLINE]
Free PMC Article

Publication types, MeSH terms, Grant support

Publication types

MeSH terms

Grant support

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center