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Trends Genet. 2008 Apr;24(4):154-8. doi: 10.1016/j.tig.2008.01.002. Epub 2008 Mar 5.

Adapting to environmental changes using specialized paralogs.

Author information

1
Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, Nova Scotia, Canada.

Erratum in

  • Trends Genet. 2008 Jul;24(7):327.

Abstract

When a bacterial species survives under changing environmental circumstances (e.g. salinity or temperature), its proteins might not function in all physicochemical conditions. We propose that prokaryotes cope with this problem by having two or more copies of the genes affected by environmental fluctuations, each one performing the same function under different conditions (i.e. ecoparalog). We identify potential examples in the bacterium Salinibacter ruber and in other species that experience wide environmental variations.

PMID:
18325625
DOI:
10.1016/j.tig.2008.01.002
[Indexed for MEDLINE]

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