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Dermatol Online J. 2008 Jan 15;14(1):6.

An unusual presentation of atypical fibroxanthoma.

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  • 1Department of Pathology, Baylor College of Medicine, USA.


Atypical fibroxanthoma (AFX) is a rare cutaneous spindle-cell neoplasm. The tumor occurs most commonly in sun-damaged skin of the head and neck in elderly patients. A small subset of patients (approximately one in five cases) is middle-aged and presents with AFX of the trunk or extremities in areas without evidence of actinic damage. We report an unusual case of AFX of the lower leg in an 81-year-old woman with extensive actinic damage.

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