Format

Send to

Choose Destination
See comment in PubMed Commons below
Bioinformation. 2008 Jan 27;2(6):249-52.

Evaluation on the combined effect of Sesamin and Schisandra extract on blood fluidity.

Author information

1
BRAND'S Centre for Health and Nutritional Sciences, Cerebos Pacific Limited,18 Cross Street # 12-01/08, Singapore. danieltsi@yahoo.co.uk

Abstract

Several studies have demonstrated a link between blood viscosity and various forms of liver dysfunction. Therefore, we investigated the effect of liver protective herbal materials, Sesamin combined with extract of Schisandra chinensis berry (Schisandra) for its potential to improve blood fluidity in humans. Ten human subjects were recruited to study the effect of sesamin combined with schisandra extract (SCH) for two weeks on blood viscosity. Blood fluidity was measured as the transit time for 100mul of heparinized whole blood to pass through a micro-channel array setup at baseline, 1 week and 2 weeks. For safety assessment, blood biochemistry, hematology and urine analysis were taken at baseline, 1 week and 2 weeks after SCH administration. No safety concern and adverse effects were observed during the 2-week continuous intake period. Intake of SCH reduced blood passage time by 9.0% and 9.7% at 1 and 2 weeks, respectively. In conclusion, this pilot clinical study indicates that the combined administration of sesamin with schisandra extract could improve blood fluidity after 1 week of oral intake and this effect was sustained up to 2 weeks.

KEYWORDS:

Schisandra chinensis; blood fluidity; blood passage time; micro-channel array; sesamin

PMID:
18317575
PMCID:
PMC2258427
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Support Center