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Spinal Cord. 2008 Jul;46(7):517-22. doi: 10.1038/sj.sc.3102167. Epub 2008 Mar 4.

Treatment of neurogenic bowel dysfunction using transanal irrigation: a multicenter Italian study.

Author information

1
Neuro-Urology Spinal Unit, University of Florence, Florence, Italy.

Abstract

STUDY DESIGN:

Thirty-six patients with unsatisfactory treatment of neurogenic bowel dysfunctions (NBD) were enrolled from Spinal Units and Rehabilitation Centers in Italy. Treatment was for 3 weeks using a newly developed integrated system with an enema continence catheter for transanal irrigation (Peristeen, Coloplast A/S Kokkedal Denmark).

OBJECTIVES:

To evaluate the effects of Peristeen Anal Irrigation on NBD and patient quality of life (QoL).

SETTING:

Italy.

METHODS:

Lesion level, ambulatory status and hand functionality were determined in all patients. NBD symptoms and QoL were evaluated before and after treatment, using a specific questionnaire. Statistical analysis was performed using McNemar Test and Sign Test.

RESULTS:

Thirty-six patients were enrolled, and 32 patients completed the study. At the end of the treatment, 28.6% of patients reduced or eliminated their use of pharmaceuticals. Twenty-four patients became less dependent on their caregiver. There was a significant increase in patients' opinion of their intestinal functionality (P=0.001), QoL score (P=0.001) and their answers regarding their degree of satisfaction (P=0.001). A successful outcome was recorded for 68% of patients with fecal incontinence, and for 63% of patients with constipation.

CONCLUSION:

Peristeen Anal Irrigation is a simple therapeutic method for managing NBD and improving QoL. It should be considered as the treatment of choice for NBD, playing a role in the neurogenic bowel analogous to that of intermittent clean catheterization in bladder treatment.

PMID:
18317488
DOI:
10.1038/sj.sc.3102167
[Indexed for MEDLINE]

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